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mutations offered The point that, as described beneath, CLL therapy is predicated over the presence or absence of those mutations. The current consensus is always that, aside from clonal mutations, subclonal mutations having a variant allelic frequency ranging from five to 10% (and therefore beneath the brink of detection by regular molecular tactics) is also described, Whilst Individuals which has a variant allelic frequency LINK ALTERNATIF MBL77 lower than five% mustn't, but there is much controversy close to these troubles and this recommendation may well change in the future.
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